16 years of clinical expertise: Helena Rubinstein sustains and elevates your medico-aesthetic results through the intelligence of the integrated protocol.
By combining cellular science and medical expertise, Helena Rubinstein establishes itself as the benchmark luxury anti-aging partner, capable of acting on the trajectory of skin aging in perfect synergy with aesthetic procedures. For Helena Rubinstein, Excellence is not a mere destination, but a perpetual scientific pursuit. Its core conviction: the skin is not a passive tissue, but a living organ whose fundamental unit is the cell. Understanding the complex mechanisms at the heart of the cell forms the foundation of HELENA RUBINSTEIN CELLULAR SKIN SCIENCE.
The approach is no longer limited to correcting the visible signs of time; it aims for a pioneering objective: reconfiguring skin cells to restore them to an optimal state of health and youth, precisely targeting cellular repair, inter-communication, and reprogramming.
To continually push the boundaries of skin science, Helena Rubinstein surrounded itself with an international Scientific Committee in 2025. This choice extends the visionary heritage of Madame Helena Rubinstein, a pioneer of avant-garde collaborations since 1902. Today, the brand teams up with global luminaries—scientists and physicians— to shape the future of skincare as a companion to procedures.
EXPERTS’ PERSPECTIVE: COSMETICS AS A MEDICAL PILLAR

For the Helena Rubinstein Scientific Committee, cosmetic skincare is a fundamental pillar. Systematically integrated before, during, and after aesthetic procedures, it guarantees accelerated repair and maximises clinical results. This synergy relies on a triple complementarity:
- Temporal complementarity: Where aesthetic medicine offers instantaneous and targeted correction, precision cosmetics take over on a daily basis to sustainably maintain the skin’s natural mechanisms.
- Empowerment: Aesthetics procedures can sometimes feel passive. The integration of a daily cosmetic protocol rede nes this experience, transforming the patient into an active protagonist in her own beauty and recovery.
- Global optimisation: Prior to procedures, treatments prepare and strengthen tissues; afterwards, they accelerate repair. This synergy visibly ampli es results and helps sustainably space out the need for clinical interventions.
REPLASTY: THE ART OF THE “COSMETIC BANDAGE” PUT TO THE TEST OF FIGURES

It is through exclusive partnerships with aesthetic clinics that HELENA RUBINSTEIN enriches its medical knowledge of the skin, postintervention needs, and the latest trends in repair protocols. Born in 2008 from the historic collaboration between Helena Rubinstein and Dr. Michel Pfulg, founder of the prestigious Laclinic-Montreux, the REPLASTY range embodies the pinnacle of recovery skincare. Inspired by post-operative bandages, it combines radical sensoriality with undeniable clinical efficacy: Applied in preparation for and recovery from eyelid surgery, the Replasty Eye Bandage treatment significantly reduces clinical side effects (redness, puffiness, bruising), promoting accelerated healing and optimised long-term results1.
The Age Recovery Night 50PX cream, tested in synergy with Micro-focused Ultrasound – MFU, demonstrates:
-32% sagging of the facial oval after a single session (compared to -17% with a neutral cream).
+20.14% firmness on the cheekbones (compared to 9.29% without the Replasty formula).
Used in a duo with radiofrequency microneedling (RFMN) treatment, the Replasty Age Recovery Day [GR] Day cream multiplies the benefits compared to a neutral cream4: plumper skin (x 1.9), cheekbone volume (x 2.2), reduction of forehead wrinkles (x 2.7), and improved firmness (x 2.1). 100% of women confirm acceleration and prolongation of aesthetic procedure anti-aging efficacy compared to 82% associated with neutral cream associated with RFMN. In 2026, Helena Rubinstein is taking a new step by partnering with Dr. Kyungkook Hong, a global expert in cellular therapies (stem cells and exosomes). This collaboration inspired revolutionary [EXO]SAMTM technology into the heart of the new Powercell Skinmunity [EXO] Serum, confirming its role as the ideal ally in association with skinboosters.
By combining advanced aesthetic medicine with exclusive innovations—such as high-purity Pro-XylaneTM MADE IN FRANCE (invented, formuled, produced in France) and nano-vesicles of Crithmum maritimum native cells—Helena Rubinstein offers professionals powerful solutions to ensure robust cellular repair, restructure facial contours, regenerate the skin, and boost posttreatment efficacy.
Dr. Audrey Gueniche, HELENA RUBINSTEIN. Global Scientific Director.

Doctor in Pharmacy and holder of a PhD in skin biology, she has a distinguished career ranging from in vitro studies, clinical trials, open innovation to development, pursuing the brand’s long-standing avant-garde research and science.
References
1. Clinical test (12 subjects): blepharoplasty, half-face application vs. neutral cream (2x/day, 2 months pre-op then from D7 post-op for 2 months).
2. Clinical test (14 subjects, Laclinic Montreux): 28 days of pre-treatment, 2 sessions of Ulthera®, and 84 days of post-treatment.
3. Clinical test (2 groups of 44 subjects, Sichuan Univ. Hospital, China): 2 days of pre-treatment, 1 session of PENINSULA®, and 42 days of post-treatment.
4. Clinical test (2 groups of 40 subjects): 3 radiofrequency microneedling (RF MN) sessions over a total of 5 months (comparison of neutral cream vs. Replasty Age Recovery Day [GR])
