By Doctor Riekie Smith

A protocol that improves skin quality by injecting into each skin layer

Peels, lasers and micro-dermabrasion are, in most cases, the most common skin rejuvenation procedures. As a complement, treatments such as mesotherapy focus on revitalising the skin and enable us to slow down skin aging. Today, weakly-reticulated fillers are available, which supplement these revitalisation protocols by smoothing superficial wrinkles.

For optimum results, I have created the “Bio Skin Gineering” protocol, which enables us to treat every layer of the skin for complete rejuvenation.

What products do you use in the Bio Skin Gineering protocol?

I use NCTF 135 HA, which I associate with a weakly-reticulated hyaluronic acid.

What type of patients is it for and what are the indications for this protocol?

The Bio Skin Gineering protocol enables us to improve the appearance of skin that has been damaged by solar elastosis and to treat photo-aging in the face, neck, décolletage and hands.


What is your take on skin aging?

Skin aging occurs at all different levels, from the most superficial layers to the deepest layers of the skin.

  1. Epidermal

A dehydrated and wrinkled superficial skin layer is proof of low hydration levels and slow cell renewal.

  1. Dermal-epidermal junction

The base layer of the epidermis is in contact with the deep dermis. A nutrient exchange occurs at this layer, from the vascular dermis to the avascular epidermis.

  1. Dermal

The level of hydration and the health of the cells and the extracellular matrix contribute to the functionality and quality of the dermis. The quality and quantity of glycosaminoglycans (collagen, elastin and hyaluronic acid) are determining factors of aging.

  1. Sub-dermal (superficial fat pads)

The superficial fat pads support the dermis. A loss of this fat makes wrinkles more visible and the dermis more dehydrated.

By making sure that all of the skin’s layers are treated and densified, we can effectively reduce the consequences of skin aging.

Could you describe your approach and the techniques that you use? 

I follow 4 steps in order to treat each skin layer :

Step 1: Epidermal rejuvenation:

30G needle x 13mm

< 10-degree angle to skin

Product used: NCTF 135HA

Step 2: Rejuvenation of the dermal-epidermal junction  

Papule technique

30G/32G needle x 4-6mm

< 30-degree angle to skin

Product used: NCTF 135HA

Step 3: Intra-dermal rejuvenation

Multi-puncture technique

30Gx4mm ou 32Gx4mm needle

45-degree angle to skin

Product used: NCTF 135HA

Step 4: Sub-dermal rejuvenation 

Superficial fat pads

27G needle or according to filler density

> 45-degree angle to skin

Product used: weakly reticulated hyaluronic acid

How would you sum up your Bio Skin Gineering protocol?

Bio Skin Gineering is a combination of techniques that enables us to thoroughly rejuvenate the different layers of the skin.

It is the ideal treatment for wrinkled, dehydrated or dull skin that needs a boost.

Bio Skin Gineering is particularly suitable for treating the peri-orbital and peri-oral areas, the neck, the décolletage and the hands. The skin looks more radiant immediately after treatment. After four sessions, the skin is better hydrated and its texture is improved.


What are your tips for a successful Bio Skin Gineering treatment?

  • Prior to treatment, I apply an anaesthetic cream so that the procedure is more comfortable for the patient.
  • I start with the deepest technique and finish with the most superficial layers.
  • I round off the treatment with a deep massage using a suitable product, such as B3 Recovery cream from SKIN PERFUSION.


Doctor Riekie Smit

Aesthetic practitioner, South Africa

International tutor and university professor. She designed the first higher-education diploma for aesthetic medicine in her home country. She is also president of the AAMSSA, the Aesthetic and Anti-aging Medicine Society of South Africa.




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