mesofiller® nexha combines cross-linked hyaluronic acid and succinic acid, allowing immediate structural correction as well as progressive biostimulation.
Dr. Beatriz Beltrán reveals all the secrets of the new era of skin rejuvenation.
Understanding skin aging through neostimulation
What is senescence and how does mesofiller® nexha act against aging at the cellular level?
Cellular senescence is the process that explains the progressive loss of fibroblast functionality, responsible for collagen production. With mesofiller® nexha, we act directly on this phenomenon and other key mechanisms of cellular aging, such as mitochondrial dysfunction and altered intercellular communication.
How can mesofiller® nexha help fight skin aging?
mesofiller® nexha prolongs collagen stimulation thanks to the combination of hyaluronic acid and succinic acid, thus ensuring sustained regeneration of this protein and other essential components of the extracellular matrix, responsible for skin firmness and elasticity.
What is neostimulation and when do the effects become visible?
Neostimulation is an innovative concept that not only activates collagen production but also prolongs its effects over time. mesofiller® nexha combines immediate correction through cross-linked hyaluronic acid and progressive stimulation thanks to the slow release of succinic acid as the filler degrades. This allows continuous improvement of skin quality.
What is the role of succinic acid in the formulation?
Succinic acid has biological properties that stimulate various cellular functions. In combination with hyaluronic acid, it promotes collagen synthesis, mitochondrial renewal (mitophagy), and adipogenesis stimulation. This synergy has shown regenerative effects on senescent skin cells. Thus, its action goes beyond simple tissue filling and helps biostimulate the key processes underlying skin aging. These results were recently published in the prestigious International Journal of Molecular Sciences.
How do succinic acid and hyaluronic acid work against cellular aging?
Both actives act complementarily on essential processes of skin aging. Succinic acid plays a role in regulating the cell cycle, mitochondrial function, and oxidative response, while hyaluronic acid improves hydration and extracellular structure. Together, they help counteract cellular senescence, oxidative stress, and loss of intercellular communication.
Dr. Beatriz Beltrán, aesthetic doctor with more than 17 years of experience and Director of BB Clinic in Barcelona. She has extensive expertise in combined techniques in the field of Aesthetic Medicine.
