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  • Hyperpigmentation

Aesthetic Procedures: How to Prevent Post-Inflammatory Hyperpigmentation (PIH) with the Melaflash Home Set?

  • 25th August 2026
  • Thierry PIOLATTO

An exclusive article co-authored with Dr. Arnaud Lambert, Aesthetic Physician, shedding light on the critical role of at-home care in managing pigmentation disorders.

Aesthetic medicine procedures (lasers, peels) are formidable tools for treating dark spots and evening out the complexion. However, they come with a major risk often dreaded by both practitioners and patients: Post-Inflammatory Hyperpigmentation (PIH).

It is an alarming clinical reality: the thermal or chemical trauma generated by an aesthetic procedure causes inflammation. In patients with Fitzpatrick skin types 3 to 6, nearly one in two cases triggers post-inflammatory hyperpigmentation following a procedure. In other words, the treatment intended to erase dark spots risks creating new ones through a “rebound effect.”

Faced with this observation, how can we secure procedures and guarantee patients an optimal result? The answer lies in at-home support. As Dr. Arnaud Lambert analyzes, preparing and securing the skin before and after a procedure has become an absolutely essential step in the patient journey.

The Melaflash Home Set: The Protocol that Secures Your Aesthetic Procedures

Hyperpigmentation is not only treated on the day of the procedure in the doctor’s office. It requires a continuum of care. With this in mind, DERMEDEN Laboratories developed the Melaflash Home Set. It is a true at-home support protocol designed for three key stages:

  1. Before the procedure (Preparation): It puts melanocytes to “rest” and limits the skin’s inflammatory response to the trauma.
  2. Between sessions (Maintenance): It actively continues to reduce background hyperpigmentation.
  3. After the procedure (Securing): It blocks the post-traumatic inflammatory cascade, thereby preventing the onset of PIH.

An Expert Synergy in 3 Products

The secret of this set lies in a targeted synergy addressing all mechanisms of inflammation and pigmentation:

  • Anti-Dark Spot Concentrate (5% Tranexamic Acid + 10% Niacinamide): The “game changer” of the protocol. Tranexamic Acid (TXA) offers a unique double lock: it inhibits tyrosinase (pigment pathway) and blocks plasmin activation (vascular and inflammatory pathways). Niacinamide prevents the transfer of remaining melanin.
  • Mild Home Peeling (20% Encapsulated Glycolic Acid): Gently exfoliates, eliminates pigment-loaded dead cells, and prepares the skin without causing irritation.
  • Retinoid Concentrate (Stabilized and Encapsulated Retinoids): Stimulates epidermal renewal and strengthens overall depigmenting action with optimal tolerance.

Undeniable Clinical Results

Approved for all Fitzpatrick skin types, this protocol demonstrates exceptional clinical results over 84 days:

  • Up to a 30% reduction in melanin levels and a spectacular drop in the MASI score reaching -93%.
  • Boosted skin radiance (+267% luminosity after 84 days).
  • 0% adverse effects and 96% excellent skin tolerance.

A comprehensive approach acclaimed by doctors, ideal for preparing high-risk skin, prolonging depigmenting treatments, and soothing inflamed skin.

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Thierry PIOLATTO

Previous Article
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  • Hyperpigmentation

Aesthetic procedures: How can the risk of post-inflammatory hyperpigmentation (PIH) be prevented with the Melaflash Home Set?

  • 25th August 2026
  • Thierry PIOLATTO
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